Giant Condylomata Acuminata of Buschke-Lowenstein Associated With Paraneoplastic Hypercalcemia

Giant Condylomata Acuminata of Buschke-Lowenstein Associated With Paraneoplastic Hypercalcemia

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Low-risk human papillomavirus types 6 and 11 can manifest as giant apac1/60/1/cw condylomata acuminata (GCA) of Buschke-Lowenstein.Up to 50% of GCA can slowly progress over years to fungating, invasive tumors.The malignant potential is attributed to unique immune evading abilities of the human papillomavirus.A 42-year-old male presented with pain and foul-smelling discharge from his genital warts.The histopathological examination of the mass showed invasive squamous cell carcinoma, and it was associated with paraneoplastic hypercalcemia.

The timely removal of long-standing GCA in order to rosy teacup dogwood prevent a carcinomatous transition is a priority.